CATTLE is an integrated cancer treatment resource with linked evidence from a comprehensive set of heterogeneous data sources. Users seeking information for approved or potential cancer drugs can use CATTLE as a one-stop web portal, since CATTLE collects and integrates different types of information across the full-spectrum of a drug development cycle (from pre-clinical studies to post-market surveillance).
CATTLE currently catalogues146 FDA-approved drugs and 2,176 candidate drugs in clinical trials associated with 108 types of cancers and 12,584 genes. Users can query the database using drug names, cancer types, gene names or gene variations, to obtain summaries of topics of interest in an effortless way. Links to a comprehensive list of external resources are also provided as evidence, allowing users to quickly access and investigate prior research results. Currently CATTLE integrates more than 35 different data sources, such as general drug knowledge bases (e.g., DrugBank and KEGG Drug), pharmacological information sources (e.g., drug@fda and NCI Thesaurus), pharmacogenomics databases (e.g., PharmaGKB, CCLE and GDSC), literature (MEDLINE), patents (USPTO), phamacovigilance data (e.g., FAERS), adverse reaction data (SIDER), and clinical trials (ClinicalTrials.gov).
Being the first integrated data source containing an extensive list of cancer drugs linking to the full-spectrum of available information, CATTLE is expected to be a valuable resource for cancer treatment research.
Terms and Conditions of Use
By using this website, you agree to the following terms and conditions:
- The information provided in this website is for general scientific research purposes only. They are not to be used for the provision of medical advice.
- While CATTLE is freely available for use by any individual, please reference this website if the data is used in another product or service.
- The information in CATTLE has been aggregated from various sources (please see the Resources section for details). While we endeavor to keep the information updated and accurate, we make no guarantees of any kind, either explicit or implied, about the completeness, accuracy, reliability, suitability or availability of the data in the website for any purpose. Any reliance on the information therefore, is strictly at your own risk.
- In order to continue development and ensure optimum functioning, we will track the usage statistics of CATTLE via Google Analytics.
- CATTLE developers are not liable to the user for any loss or damage of any kind, either direct or consequential. While every effort is made to have the website running smoothly, we do not take responsibility for the website being temporarily unavailable due to issues beyond our control.
- CATTLE is developed by the Center for Computational Biomedicine at School of Biomedical Informatics of the University of Texas Health Science Center at Houston.